Parkinson's disease (PD) is one of the most common neurodegenerative disorders. Although the cause of PD is not known, genetic and environmental factors are strongly considered to be the main determinants and also family history is a risk factor. Studies strongly suggest that exposure to pesticides, well water consumption, rural living, anonnacin (a sour-sop component) and other chemicals such as a synthetic opiate, 1-methyl-4-phenyl-1,2,3,6-tetr ahydropyridine (MPTP) are some of the predisposing environmental factors leading to Parkinson's disease. These factors trigger a complex of pathogenic events which lead to death of neurons called the dopaminergic nigral neurons in the brain. [More...]
Friday, February 6, 2009
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